In the context of the COVID-19 pandemic, it is of the utmost importance to accelerate the discovery and development of safe and more effective drugs and vaccines. Therefore we offer companies, research institutions and clinics an exchange platform for the search for partners, technologies and expertise in the context of COVID-19 research projects.
-> To the projects of the BioM-COVID-19 platform.
a) We publish here your inquiry or offer.
b) If the project is to be treated confidentially, we will be happy to take your suggestions and connect you with suitable partners from the academic or industrial sectors.
We would also like to draw your attention to the following contact points/information.
4G Clinical is offering global RTSM / IRT / IxRS / IWR services to bringing crucial medicines to those who need them, faster.
Climedo Health offers its web-based platform for clinical data collection including digital patient diaries free of charge for medical practices, clinics, research institutes and non-profit organizations doing research related to COVID-19 (Coronavirus) / SARS-CoV-2. Climedo’s predefined digital eDiaries and ePROs (“electronic Patient Reported Outcomes”) will allow test subjects to submit potential symptoms, side effects or information on their state of wellbeing remotely via a mobile device or computer, even while being quarantined.
CTI is very interested in sharing our experience with companies that are planning therapeutic clinical trials in Covid-19 patients or that want to test Covid-vaccines.
CTI is a global full-service mid-size CRO founded in 1999.
We are a leading Clinical Research Organization in the Covid-19 space with over 15 projects running in US, Europe, South America and Asia through our 30 offices worldwide. This includes therapeutic trials and vaccine studies. Press releases to several projects can be found on our website, f.e. a first publication on a successful application of Humanigen's antibody Lenzilumab on the neutralization of GM-CSF in Covid-19 patients with severe pneumonia.
CTI services cover all steps involved in planning and conducting clinical trials, as well as, strategic regulatory support with early authority meetings, synopsis and protocol development.
Our team of medical officers include experts in general medicine, hemato-oncology, transplantation, kidney, liver, lung disease, neurology, and ophthalmology. Our deep knowledge in immunology and pulmonology is extremely useful in Covid-19 related trials.
Pandemic response calls for speed in clinical development of vaccines and treatment options. The FDA expedites its protocol review time to 24 hours in order to enable this. We help sponsors develop innovative adaptive study design with very rapid turn-around (24-48 hours), enabling fast review and regulatory engagements. With our global network of acute care experts we also help sponsors connect to investigators.
Our COVID experience include designs of post-exposure prophylaxis study, outpatient platform trial, vaccine, ICU respiratory device as well as national epidemic planning.
FGK Clinical Research is a full-service CRO based in Munich with subsidiaries in Berlin, Prague, Warsaw and Budapest. We have over 18 years of experience in managing clinical studies of phases I to IV in various therapeutic indications throughout Europe. Currently, we are involved in several COVID-19 projects.
Clinical Research Services for national and international clinical research with drugs and medical devices in Full- or Partial-Service :
The generation of either medicinal products or medical devices requires consolidated regulatory expertise and the consideration of corresponding requirements from the beginning of development. We identify the optimal strategy for your product, compilation of the investigational medicinal product dossier (IMPD – Quality, Clinical, Tox.), the Clinical Evaluation Plan (CEP) or the clinical evaluation report (CER) and can apply for the conduction of the clinical trial at the agencies and ethics’ committee. Depending on your needs we will find a tailored solution for your developmental product.
Support regarding CE marking of medical devices and IVD medical devices:
We offer to consult you 15 min free of charge, how to assess sensitivity in a fast approach and how to place your product on the market under "emergency use authorization".
Tag your message with @IVD and you will be forwarded to the IVD team by our dispatchers.
We offer rapid & high quality support of COVID-19 studies: Statistical consulting, eCRF setup & clinical data management. We’ll donate all fees from statistical consulting for COVID-19 studies to the University Hospital in Essen (https://spenden-für-corona.de)
Working on a COVID-19 trial since end of March 2020, our team is familiar with what is needed most now: Exceptional commitment and performance, going beyond expectations and industry standards to make critically important projects feasible within very short timelines.
Profil is stepping up to this responsibility by offering support to companies developing vaccines against COVID-19. As one of the leading phase 1 units in Europe, we can offer experience with Europe's regulatory landscape as well as years of routine in conducting early phase trials in our two clinics in Germany. Combined with our team's previous experience working on novel vaccine developments this allows us to support companies looking for rapid and effective support in their clinical development.
Proinnovera is available to manage clinical research projects related to COVID-19. We have over 20 years of experience in providing the following services in various therapeutic areas including vaccination studies:
ageneo set up a campaign to meet the challenging requirements of companies working on COVID-related projects.
In order to contribute from our side to this great task of finding solutions, therapies, diagnostics, and vaccines for COVID-19, we offer our recruitment expertise for both permanent placement and freelancers for a dramatically reduced fee.
We offer our service Recruiter on demand (ROD) on a full service level for free for startups/SMEs working on COVID-19 projects.
We take care for all administrational aspects of your recruiting process, select potential candidates, screen them with a telephone or video interview. Additionally, we plan and accompany your interview process until the final decision and the offer process. With our service your time and effort are dramatically reduced, as many steps are automated by a recruiting software or through our work. With your personal login you can always oversee the status of the recruiting process and decide about next steps.
The Biomax Offering in the field of COVID-19 research activities consists of three parts:
Building up a human Coronavirus Disease Map to support SARS-CoV-2 pathobiology research and vaccine development by combining literature mining with expert curation and semantic data integration.
Providing a knowledge management solution for integration of clinical, laboratory, imaging and high-throughput experimental data with prior knowledge from structured databases and literature mining.
We currently seek partners either interested in contributing SARS-CoV-2 specific data or looking for integrated data and knowledge resources for integrative analysis and machine learning.
We offer research projects the possibility to use our database software for clinical studies and database development.
We can also support projects with our knowledge in software development and big data analysis. Depending on the application a prototype can be provided by us within a few days free of charge.
1. Online Image Annotation Tool for free
2. Develop computer vision AI
MDs, researchers, medical labs, clinics, scientists, data engineers – if you need an image annotation tool to fight #coronavirus and label e.g. x-ray images, then we offer our platform www.datagym.ai for FREE.
We also offer to develop computer vision AI for diagnostic purposes for FREE if you can provide images.
We want to help and offer our expertise. eXXcellent and Intuity are strong partners when it comes to cover the entire field from exploration, software- and hardware prototyping to market-ready software and development of products.
Exploration & Advanced Development
Productive Software Development
Dr. Kristin Kaltdorf, Software Engineer, kristin.kaltdorf@, Tel: +49 - 151 4022 9746, exxcellent.dewww.exxcellent.de
Bettina Maier, Exploration & Design Strategy | Fellow, maier@, Tel: intuity.de
+49 - 711 94 54 55-74, www.intuity.de
We are looking for partners from pharm industry for drug development and medical partners from university/hospital for diagnosis and research. COVAI-1 is a software infrastructure, an autonomous AI system for diagnostics, prevention, information, detection system and drug research against corona virus. This system supports medical experts by decision making. It creats reproducible and objective results and gives to medical experts the possibility to train their own AI without programming knowledge and is able to train and volidate themself by adding new information. It runs in a cloud by using low power laptops or secured in a lab at a workstation or at an internal infrastructure of it.
We offer a team of data scientists with expertise in biomedical field (bioinformatics, image processing, biostatstics, and machine learning and statistics in general).
In our research group, we have extensive experience in high-throughput data analysis, in particular for sequencing and network data. A main research focus is the development of bioinformatics methods for transcriptomic analysis of virus-infected cells.
We can offer support for:
Contact: Prof. Dr. Caroline Friedel, Research Group Leader, caroline.friedel@, bio.ifi.lmu.dewww.bio.ifi.lmu.de/mitarbeiter/caroline-friedel/forschungsgruppe/index.html
We are looking for partners, and offering technology and capacities of computing power.
We are a Joint Venture of cloud computing providers and data centers which want to provide our combined computing power to biotechs, universities, scientists etc. which are fighting corona.
COVID-19 Drug Repurposing Datasets Now Available in Collaboration with Vectorspace AI, Amazon & Microsoft’ prn.to/34k2zns
Vectorspace AI focuses on context-controlled NLP/NLU (Natural Language Processing/ Understanding) and feature engineering for hidden relationship detection in data for the purpose of powering advanced approaches in Artificial Intelligence (AI) and Machine Learning (ML). Our platform powers research groups, data vendors, funds and institutions by generating on-demand NLP/NLU correlation matrix datasets. Those alternative datasets are designed for predicting unique hidden relationships between objects such as genes, proteins, drug compounds or infectious diseases. Our objective is to enable any group analyzing data to save time by testing a hypothesis or running experiments with higher throughput. This can increase the speed of innovation, novel scientific breakthroughs and discoveries.
We are able to quickly (0-2 days) deliver (sell or rent or provide for free during the crysis period) a refurbished ABI 7300 or 7500 or 7500-Fast Real Time PCR device from our stock to labs, who want to increase their Corona test capacity
Since 1989 “AID Autoimmun Diagnostika” with its headquarters in the south-west of Germany (Strassberg), produces and markets diagnostic products, imaging devices and suitable software programs within the wide range of immunology and infectious diseases. One of the world-wide most used EliSpot readers (AID EliSpot Reader System) was developed and is being produced by AID.
Since 2017 our dedicated contract research laboratory “Immune Analytics” (IA) located in Strassberg offers immune analytical services for preclinical and clinical samples with prime focus on our vast EliSpot expertise. Our project staff possesses own regulated immunotherapy development expertise which we transform into a successful support of your own projects. We have established COVID19 EliSpot assays as well as peptide arrays (both research use) which can be applied in context of regulated pre-/clinical studies (GCLP).
Biotrend Chemikalien GmbH, the German Office of the European Cliniscience-Sales-Group, is offering sensitive and specific CE-IVD certified RT-PCR kits (FDA and EUA approved), Viral RNA-Extraction Kits, Rapid IgG/IgM tests, Virus Transport Medium (VTM), sample collection vials and swabs for COVID-19 diagnostic.
We are offering our technological and bioinformatic expertise for the development of comprehensive IT platforms, for handling and analyzing biomedical data gained through COVID-19 testing. We already have a partner for the laboratory preparation of samples. The laboratory equipment is currently expanded to scale-up the workflow.
We are an international distributor with a global partner network. We can provide more than 20 Million products of more than 140 partner companies around the world. We now offer CE IVD certified COVID-19 detection kits for diagnostics.
We are sponsoring a small pilot study, looking for a clinical partner that can quickly address and run the clinical study. We will provide the home anti-body testing, and IT platform for analysis.
As a leading provider of reliable and innovative products and services to the Life-Science, Diagnostic and Pharmaceutical community, we are offering various COVID-19-related genomics and proteomics products.
I:O:I Investment is a research company based in Hungary and the manufacturer of a novel colloidal gold nanoparticle which could be used for covid-19 tests.
The characteristics of our particle: 98.2% percent of them is 119.8nm, however we can easily shift the size of the particles either way.
It is a purple coloured crystallised derivative of fulvic acid, it’s called the “Purple of Konth”, a stable and water-soluble colloidal gold nanoparticle, fully characterised by melting point, FTIR and 13C-NMR spectra. Gold fulvate retains its special purple colour in all dilution.
The Mediagnost Anti-SARS-CoV-2 ELISA E111-IVD is a highly specific enzyme immunoassay for the detection of IgG antibodies against the SARS-CoV-2-S1 receptor binding domain (RBD) in human blood. The test has been CE marked since May 6, 2020.
The Anti-SARS-CoV-2 ELISA is produced and sold by Mediagnost and is now available to diagnostic laboratories that have established the appropriate facilities to carry out the ELISA technique.
Mediagnost specializes in developing ELISA systems and producing these as test kits: e.g. for Growth Factor, Leptin, and antibodies against Hepatitis A-Virus or Pseudomonas aeruginosa.
Microcoat offers the analysis of infectious disease relevant biomarkers, e.g. cytokines on various platforms. We have multiplex panels established on ELLA, MSD and Quanterix platforms.
We have established the Simple Plex COVID-19 Cytokine Storm Panel suitable for measurement of key inflammation markers that are indicative of pathologic inflammatory response.
Benchmark and selection of platforms for the evaluation of new potential biomarkers in early phase and pre-clinical development.
Routine analysis of validated biomarkers in clinical phase (GCP).
We are offering expertise in development and manufacturing of ELISA as well as Lateral Flow Assays.
Microcoat is available for cooperation projects for developing diagnostic assays. Based on established technologies and material platforms we offer rapid development with subsequent large-scale manufacturing capabilities (Bulk materials, ELISA and Lateral Flow Tests).
Contact: Dr. Mark-Steven Steiner; Dr. Harald Waltenberger, Director Diagnostic Raw Materials; Director Development, m.steiner@; microcoat.deh.waltenberger@, Tel: +49-8158 9981 32, microcoat.dewww.microcoat.de
We offer advanced technology for digital mass screening. With its digital healthcare platform myoncare, ONCARE GmbH provides a technical solution for mass screenings. Using a generic QR code, users can register anonymously in the app and complete the screening questionnaire stored there. Based on the score determined from the questions, recommendations for action are automatically made to the user in cooperation with doctors.
Plazus Technologies is a development service provider that also developed a product that is a dedicated communication app for private groups to communicate. Everyone involved in the group, to securely share private information about individuals using blockchain technology.
We would like to extend our protocol and provide the ability to give secure and accurate information and up to date on someone's health history and status.
Quarano is used to collect data and document the epidemic management of health authorities by digitizing the work steps as well as self-reported quarantine cases and suspects. The application is not used for diagnosis or therapy of index or contact cases.
We are affiliated with the #wirvsvirus solution enabler by the German Chancellery and are currently testing our software with one of Germany's largest regional healthcare administration.
We are looking for partners regarding the operations and IT operations of our cloud solution, additional capacities for software development, and organizations willing to work with us and test our software.
We offer production capacities for the mass production of lateral flow tests.
We`re looking for partners to develop corona-virus piont of care rapid tests.
We are experts in detecting analytes in saliva or sputum.
We are experts in saliva/ blood/plasma sample preparation for lateral flow tests.
We offer a state-of-the-art handheld device for the electronic readout of lateral flow tests.
We have and offer our know-how and experince of 25 years in developing and producing lateral flow tests.
We are supporting diagnostic manufacturers to get their COVID-19 tests on the market soon according to the EU In Vitro Diagnostic Directive, the new EU In Vitro Diagnostic Regulation and US-FDA regulations.
One of the main limitation of detection methods like PCR is that when a sample is taken for PCR-COVID-19 testing, the sample often contains a lot of background of biological materials from the patients, PCR is very sensitive to the purity of the sample to be amplified to have reliable results. So it is harder to identify the RNA of the virus against interferences of other biomolecules from the patient. This means that the PCR analysis takes longer and may lead to false negatives.
Our technology based on SPE disks is a thin and soft membrane (0.6mm of thickness) which can be adapted to diverse applications to collect contaminants. Our technology is applied routinely for sample preparation in bioanalysis, proteomics and environmental analysis:
We offer strategies, workflows and analysis in Mass Spectrometric Non-Target Screening of Drugs and Active Ingredients in products or production processes.
Non-target screening (NTS) is a universal technique that can be applied in many areas, such as drug production and the screen for ‘Non Intentionally Added Substances’. The occurrence of unexpected molecules (e.g. impurities, fake compounds and others) cannot be characterized with classical (quantitative) ‘multi residue monitoring’. NTS can be conducted in parallel to already implemented approaches, like drug quantity and simultaneously screen for unexpected or unknown compounds. This can be beneficial for all kinds of production processes or active ingredient analytics. If you need to monitor your drugs and products for security and quality reasons we will help you with our NTS analysis.
BRAND products for RT-PCR:
BRAND products for ELISA / antibody tests:
FLUICS CONNECT is offering a flexible inventory management solution to label and track samples. Based on a mobile app and a cloud-connected label printer our system can be very quickly installed – everywhere labeling samples with smear-proof cryo labels and QR codes is needed. New labels can pe printed from the mobile app and are immediately registered in an online workspace, accessible by many collaborators.
We are developer and producer of industrial, medical and laboratory equipment according to customers orders. So we are certified according to DIN EN ISO 13485: 2016 and DIN EN ISO 9001:2015. We have special experience with sensors, electronic processing and actuators, as well as with the user interface. Our thinking is interdisciplinary and we take care of everything, as well as the device approval. We are happy to offer our services in the area of development and production of components and devices.
We offer our capacities and experience:
Manufacturing of complex turned and/or milled medical parts made of different materials (according to DIN ISO 9001:2015).
We provide laboratory services such as analytical method development and validation, quality control and stability testing of API, excipients, medicinal products, drug-related products and medical devices. We are GMP- and FDA-certified. We have a manufacturing license for the release of clinical and market batches and we can produce small batches of solid, semi-solid and liquid medicinal products as well as dry powder inhalers. We are also specialized in the development of highly innovative medicinal products with high potent API up to OEB class 5 for oral or parenteral administration to patients in the most diverse indications.
Offering expertise in the field of product development:
We offer technical support backing up your core business development.
We are offering:
• deepwell plates
• microtiter plates
• conductive robotic pipet tips
• transparent robotic pipet tips
• racked microtubes
• dispenser tips
Do you need manufacturing solutions or more capacity for your medical products? Do you need manufacturing according to the specific regulations like ISO13485 or FDA?
Zollner has been providing manufacturing solutions of complex systems to the medical industry for more than 25 years.
Offer: IF experts APPROVE above question - bionic surfaces – is in a position to arrange surface modification of non woven fabrics with potential antiviral compounds like tetrahydrozoline, chlorothiazide chloroquine and formoterol as e.g. pointed out in Pharmacoinformatics and molecular dynamic simulation studies reveal potential inhibitors of SARS-CoV-2 main protease 3CLpro; MA Alamri, MT ul Qamar, SM Alqahtani - 2020 – preprints.org
We offer a solid, high quality corona protection visor, shielding face and eyes, consisting of protective glasses fixed to a rotatable Plexiglass shield.
Further information: www.schutzvisier.online
SalamanderU link is a technology company made up of a multidisciplinary team of business experts in the life sciences industry, pharmaceutical engineering and IT.
In collaboration with Solidfog one of our regular partner, a Belgium producer and supplier of air surface decontamination systems (H2O2 nebulization), SalamanderU has the possibility to provide a solution to decontaminate masks in hospitals or elsewhere in a very short time, through the "CleanBubble", our containment chamber and the DosyMist mobile unit of decontamination of Solifog.
Denis Decubber (CBD - SalamanderU) – Via BIOWIN PLATFORM
Partners having lab infrastructure (S3 lab) and personnel to perform tests with SARS CoV 2
Partners having access to active SARS CoV 2 viruses for experiments
Expertise on quantification of viruses on surfaces.
Hardware (UV-C incl. circuitry and UV spectrometers) for irradiating samples and measuring UV light intensity.
Based on the literature other corona viruses like MERS-CoV and SARS-CoV can be successfully inactivated using UV C alone.
UV C disinfection of surfaces with potential SARS CoV 2 viruses has and is been applied already during the current crisis. However, to our knowledge, no quantitative evaluation has been reported in the literature. We propose to determine empirically the dose/inactivation curve for SARS CoV 2 for different UV-C wavelengths. Thus we expect to deduct doses that are effective for the disinfection of surfaces inside hospitals, in public transportation, elevators, etc.
Contact: Dr. Thomas Wendler, CEO, thomas.wendler@, Tel: +49 (176) 82179775 scinthealth.com
We at RAS AG developed an antimicrobial agent based on nanosilver over 15 years ago, which is now sold for various applications and is marketable compliant with the EU Biocide Regulation.
The nanosilver active substance exhibits antiviral efficacy:
Our nanosilver based formulations recently have been tested efficient against different members of the family Coronaviridae.
RAS AG offers technologies to create coatings on various substrates, that contain the antiviral substance. The active substance can be incorporated into materials for long lasting effects.
We are searching for Virologists or laboratory that have experience in the evaluating the efficacy of antiviral substances or surfaces that incorporate those substances. We are developing new products and treated articles, which include antiviral substances. The tests have to be performed with SARS-CoV-2. As result the efficacy has to be quantified at best in a certain percentage of inhibition or log-step reduction of the viral vitality/infectivity. There are different test methods available, we are open to discuss.
2bind has a broad portfolio of different biophysical analytical tools to study drug – target interactions. The range of assay cover biophysical HIT ID (HTS) via HIT validation to characterization of HITs.
Potential hits for COVID19 relevant targets could be identified and validated using different biophysical methods (MST, nanoDSF, ITC, BLI).
Biocrates is a leading supplier in Metabolomics. The technology is suitable for use in clinical biomarker research (e.g. patient stratification), as well as along the pharmaceutical R&D cycle. Biocrates’ solutions are designed to increase the likelihood of successful transfer into patient care.
Metabolism is an important component of immune regulation. Published results from research on pneumonia and sepsis provide a scientific basis for the investigation of candidate biomarkers in Covid-19. Further information can be found at https://biocrates.com/covid-19-focus/.
Key benefits of Biocrates solutions:
Biotrend Chemikalien GmbH, the German Office of the European Cliniscience-Sales-Group, is offering different 2019-nCoV and related proteins (ACE2, S protein, S protein RBD, S1, nucleocapsid etc.), cDNA, antibodies, therapeutic candidates, ELISA, RT-PCR and RNA-Extraction Kits for COVID-19 research and Vaccine development.
We are an international distributor with a global partner network. We can provide more than 20 Million products of more than 140 partner companies around the world. We are working under high pressure to continously update our webshop with products specifically for research and diagnostics on SARS-CoV-2 and COVID-19.
Cellassays GmbH offers label-free tests for efficacy of antiviral substances toward cellular models with microphysiometry.
Looking for partners:
We have coupled a 785nm Raman excitation laser into an inverted digital microscope for fast and easy single cell analysis without any labelling or staining. Due to the unique laser coupling optical trapping features are induced simultaneously that attract cells/bacteria/exosomes/viruses and hold them in position during Raman spectra acquisition. Optional fluorescence modules allow comparison with routine staining procedures.
EpiQMAx offers the analysis of antibodies and small molecules by means of mass spectrometry. In particular, we can characterize biological and biophysical parameters very precisely. Thereby, we support all research activities for COVID19 and offer our platform technology for drug discovery purposes.
What can we offer:
What are we looking for:
Contact: Dr Stefan Jungbluth / Dr Nicola Viebig, Head of Business Development / Chief Scientific Officer, stefan.jungbluth@ / euvaccine.eunicola.viebig@, Tel: +49-176-31615202 / +49-176-31615203, euvaccine.euwww.euvaccine.eu
We are offering technologies to accelerate research on covid19 projects at attractive price. In collaboration with Olink company we are offering proteomic analysis on large multiplex assay at very special rate (-50%) but also NGS on Illumina platform at reduced price.
Olink technology: 92 plex of proteins, 13 panels availables including inflammation panel to monitor cytokines strom. The technology request only 1µl of serum/plasma per panel for accurate quantification of 92 markers.
NGS: By using the latest technology (NextSeq2000) and illumina action to support COVID19 research, we are able to provide NGS services as RNA-Seq, WES at low price and rapid execution.
We are offering a label-free, impedance-based platform to monitor the host cell response in assays addressing the neutralizing capacity of antibodies against Covid-19.
Contact: Prof. Dr. Joachim Wegener, Joachim.Wegener@, Tel: +49-941-943-4546 or +49-179-4872144, emft.fraunhofer.dewww.emft.fraunhofer.de/de/kompetenzen/innovative-sensorloesungen/zell-basierte-sensorik.html, www.ibmt.fraunhofer.de/de/ibmt-kernkompetenzen/ibmt-medizinische-biotechnologie/ibmt-bioprozesse-bioanalytik.html
We are offering iPSC-based pulmonar in vitro models as target for infection studies and model system for drug discovery and substance testing. Furthermore, the possibility to perform infection studies under BSL3 conditions can be offered.
We are using human induced pluripotent stem cells (iPSCs) from young or aged subjects for differentiation into alveolar type II epithelial cells (AEC II), endothelial cells, and macrophages in order to establish a human lung model. Analyzing macrophages will characterize immunopathological alterations that accompany COVID-19. The lung models will be infected with SARS CoV-2 under BSL3 conditions to identify candidates for diagnostic markers of age specific effects as well as prognostic markers for disease severity of SARS-CoV 2 infection.
Contact: PD Dr. Claudia Claus/Dr. Matthias Jung/Dr. Antje Appelt-Menzel,
claudia.claus@, Tel: +49 - 341 97 14321, medizin.uni-leipzig.dewww.claus-lab.de, www.uniklinikum-leipzig.de/einrichtungen/virologie, www.medizin.uni-halle.de/index.php?id=6735&L=90
We can apply recombinant murine gammaherpesvirus 68 (MHV-68) as a challenge virus in mice to test the efficacy of heterologous candidate human vaccines.
Contact: Prof. Dr. Heiko Adler, Deputy Head of Research Unit, Research Group Leader, h.adler@, Tel: +49-89-3187-1327, helmholtz-muenchen.dewww.helmholtz-muenchen.de/lrr/forschung/adler-lab/scientific-focus
We are looking for partners in the field of virus research to combine our technologies and expertise for common research funding projects.
We offer versatile solutions for studying virus infection of endothelial/epithelial cells under physiologic conditions in vitro.
Examples are assays using endothelial cells under flow, lung models on air-liquid interfaces (ALI), or assays using intestinal epithelial cells.
For label-free cell killing assays, we offer a novel micropatterning technology. Using this method, single cells or cell clusters can be automatically tracked using AI-based analysis.
If you need a specialized product for your research that is not in our portfolio, please contact us and we will gladly collaborate with you.
We are offering our technology for vaccine development, viral investigations and pathogen-target cell characterization.
We are looking for partners to develop further established methods and who are in the preclinical in vitro testing of vaccine candidates.
Particular for any type of linker technology between biomolecules, antibodies, proteins etc., and small molecules. Linker can be designed that they are stable in all physiological environments or stable in plasma and fragmentize in lysosome.
Offering: Liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis of different antiviral agents and other small molecule compounds from human serum or plasma.
Therapeutic Drug Monitoring of antiviral substances for treatment of COVID-19 patients may be important in clinical studies and may offer therapeutic advantages in standard clinical care. For this purpose, quantification methods will be developed according to the following substance prioritization list:
1. Camostat mesylate, 2. Remdesivir, 3. Favipiravir, 4. Chloroquine/ Hydroxychloroquine, 5. Arbidol, 6. Ritonavir/ Lopinavir, 7. Ribavirin/ Sofosbuvir
Beyond these drug target analytes, the available technical platform could be used to quantify small molecule compounds with potential added diagnostic value in the context of severe viral infections.
Contact: Prof. Dr. med. Daniel Teupser, Director, Institute for Laboratory Medicine, Daniel.Teupser@, Tel: + 49 89 4400 - 73210, med.uni-muenchen.dewww.klinikum.uni-muenchen.de/Institut-fuer-Laboratoriumsmedizin/de/
we are a virology/molecular biology lab working on Coronaviruses for ~15 years
1) Motivated students in bioscience field with benchwork experience (molecular biology, cell culture) for internships, bachelor, masters, PhD work
2) Computer-aided drug design modellors for inhibitor modelling of our most promising coronavirus-host protein-protein interactions
3) Organic chemistry synthesis of small cyclic peptides
Contact: Dr. Albrecht von Brunn, Research group leader, vonbrunn@, Tel: +49-89-218072839, mvp.lmu.dehttp://www.mvp.uni-muenchen.de/forschung/virology/research-group-von-brunn/
We offer easy to use biophysical instruments with low sample consumption and high throughput. to measure the binding affinity of molecules to viruses. We can also measure the RNA/DNA release of viruses/virus like particles, the payload of viruses and the size of virus particles.
Our instruments allow to detect the serotype of viruses and you can measure the thermal, chemical and colloidal stability of virus particles and virus proteins. Finally, we provide technologies to optimize the formulation of vaccines and therapeutic proteins.
OmicScouts combines cell biology, biochemical and mass spectrometry-based proteomics expertise, computational biology capabilities and drug discovery experience to support drug discovery projects fast and efficient.
Expertise: cell culture media development; sourcing biochemical compounds; manufacture sterile products in industrial scale under ISO 9001 and 13485 standards.
Capacity: 10 000 L sterile filtration per week
We are looking for:
Offering profound expertise and technology for protein related vaccine and drug development;
Looking for partners in related vaccine and drug discovery development or research
QconCAT polypeptides are valuable tools for vaccine and virus research (see below). Apply QconCAT polypeptides in targeted proteomics for SARS-Cov-2/COVID-19 experiments using Q-peptides (unique proteotypic peptides) for quantification by mass spectrometry.
Custom COVID-19 protein expression or expression of protein fragments for SARS-Cov-2 (e.g. SPIKE, ORF3a, Envelope protein, Membrane glycoprotein, ORF8, Nucleocapsid phosphoprotein) or host receptors (e.g. ACE2_HUMAN)
LC-MS calibration kits to standardize workflows between experiments and across different laboratories.
Design and expression of a QconCAT protein to validate Hi3 protein quantification of influenza vaccine antigens. Smith D. et al., J Proteomics. 2016 Sep 2;146:133-40
Sciomics supports COVID-19 research with a focus on:
All assays can be complemented by a SARS-COV-2 proteome wide peptide array.
Offer: End-to-end research solutions for coronavirus SARS-CoV-2 from pathogen detection and epidemiological studies to potential vaccine development
With a comprehensive portfolio of research products, Thermo Fisher Scientific is your trusted partner for viral research and epidemiological studies to potential vaccine development:
To explore all our research tools and solutions visit www.thermofisher.com/coronavirus
To support COVID-19 research trenzyme offers following services:
Collaboration welcome & possible on development of:
We are looking for partners:
Offering consumables: Synthetic DNA / RNA products (genes, fragments, oligo pools, libraries) and NGS target capture kits.
Fully synthetic RNA positive controls for SARS-COV-2 (full genome)
SARS-COV-2 NGS Target Enrichment kits
High Throughput DNA Synthesis (DNA fragments, genes, cloned genes)
Oligo Pools, DNA Variant Libraries
Link to our COVID-19 research tools: www.twistbioscience.com/coronavirus-research-tools
Contact: Oliver Latz, NGS Sales specialist, firstname.lastname@example.org, Tel: 49-(0)162-526-843-0, https://www.twistbioscience.com
We can offer to test compounds in cell culture for toxicity and for suppression of COVID19. We are looking for partners who have components, such as new polymerase or protease inhibitors, which have not been tested so far. We have established screening for antiviral compounds in different cell culture models. In addition, we have access to a P3/S3 facility and have already obtained permission to work with wild-type COVID-19.
Contact: Prof. Dr. Jochen Bodem / Dr. Maria Steinke, AG-Leiter, Jochen.Bodem@, Tel: +49-931-3181509, vim.uni-wuerzburg.dewww.virologie.uni-wuerzburg.de/virologie/ags-virologie/ag-bodem/arbeitsgebiete/a-anti-viral-drugs/
- RT-PCR testing of samples
- SARS-CoV-2 samples, panels and positive controls
- expertise for partners
We supply human raw material sourced in our German donor centers to the IvD industry. Additionally, Biomex has set up an L2 lab facility for PCR-testing of up to 3.000 samples / day.
We are urgently looking for people who could provide:
- lymphocytes or whole blood samples from people who have been tested CoV-2 positive.
- customized synthetic peptides, length approximately 15 peptides. About 1 mg, do NOT need to be high-purified.
- fast (48 hours) HLA typing for about 5 samples, only A B C classification required
Contact: Dr. Ramona Krauss, Study Coordinator, Ramona.Krauss@med.uni-muenchen.de, Tel: +49 89 4400 52990
We offer already a well-received Multiplex Real-time PCR assay ampliCube Coronavirus Panel. In addition, we are currently developing tests for the serological antibody detection of SARS-CoV-2. This will be both a screening test in our recomWell format (ELISA platform) and a confirmation test based on a strip test (recomLine).
We would need blood samples from SARS-CoV-2 patients and also serological patient samples for SARS-1 as well as seasonal corona viruses for differentiation.
approved oral drug formulation and injectable study drug formulations for clinical trials and in vitro studies.
Request: Partners for clinical studies
Eventually: partners providing anti-viral drugs
We are looking for pharmaceutical companies or investors which have the ability to speed up the development of our new drug (currently R&D substance) against the SARS class of compounds of course as well against COVID-19 and a number of other viruses (i.e. Zika).
Delphi Genetics is focused on development and GMP manufacturing of gene therapies and especially production of plasmid DNA for viral vectors production, mRNA production, personalized medicine, API. In the context of Covid19, we could be active as plasmid DNA developer and manufacturer. Our facilities allow to produce from 10mg to several grams of plasmid DNA of different quality from R&D to GMP.
Cedric Szpirer - Executive & Scientific Director at Delphi Genetics SA Via BIOWIN PLATFORM
We are looking for partners for pre-clinical validation of the antibodies as well as for large-scale production (ideally, GMP compliant)
Request for industry collaborator in the area of siRNA design and synthesis.
Request for industry collaborator in the area of aerosol medicine.
The aim of this project is to identify target regions in the conserved areas of the SARS-CoV-2 genome to allow efficient suppression of viral replication by small RNAs and to identify formulation and delivery strategies for therapeutic administration into relevant parts of the respiratory tract.
The consortium has strong expertise in virology and nucleic acid based therapeutic approaches in virology as well as expertise in nucleic acid formulation and delivery with a special focus on pulmonary delivery of dry and liquid formulations, assessment of aerodynamic parameters and in vitro testing in air-liquid-interphase cell culture models as well as in vivo after pulmonary administration.
Prof. Dr. Olivia Merkel, Prof. for Drug Delivery, Olivia.merkel@, +49 - 89 2180 77025, lmu.dehttps://www.cup.lmu.de/pb/aks/merkel/
Dr. med. Thomas Michler, Medical specialist / Research group leader, thomas.michler@, +49 - 89 4140 6814 tum.de
We offer a medical device for the significant reduction of bacteria and viruses in the upper respiratory tract at mechanically ventilated patients.
We are looking for lab-capacities and (pre-) clinical partners to evaluate the efficacy of cold plasma against SARS-CoV-2 in-vitro. Further we are looking for clinical partners for in-vivo testing and evaluation of SARS-CoV-2 reduction and prevention of super-infections.
Vivoryon Therapeutics offers our small molecule compounds for testing of efficacy against corona virus.
We are looking for a partner with capability of testing small molecules in a disease relevant context.
CEVEC offers the CAP® cell line for COVID-19 vaccine development and production. The human suspension cell line (and derivatives thereof) has been proven in a variety of applications as a superior production cell line for vaccines, both complex peptides/ proteins as well as viral vaccines. It is particularly well suited for production of vaccines based on Adenoviral vectors, as it avoids RCA formation.
OFFER: We can provide a viral RNA vector optimized for vaccine development and administration via systemic or mucosal routes.
(1) We are looking for partners experienced in process development for GMP-conform manufacturing of viral vectors
(2) We are interested in viral vector vaccine formulation development for (i) stable long-term storage at RT or 2-8 °C and (ii) for intranasal/mucosal administration. (3) We are looking for partners to optimally design SARS-CoV-2 antigens to be expressed via the viral vaccine vector.
Scientists from the MPI of Biochemistry in Martinsried have generated Sendai virus “Semi-live” RNA Vaccines (the “vir4vac” platform) which are characterized by highest safety features. PoC of this platform was demonstrated pre-clinically with a vaccine candidate encoding the RSV-F protein. Efficient mucosal (and systemic) antibody responses and protection against challenge infections could be achieved. This RSV vaccine candidate is now ready for a phase I clinical trial. Now, we are also setting out to develop comparable vaccine candidates against the actual pandemic SARS-CoV-2 virus.
More information under: First in class “semi-live” RNA vaccines against SARS-CoV-2, RSV and other respiratory viruses
Univercells develops high-performance manufacturing technology to rapidly and cost-effectively scale-up production of COVID-19 viral vaccines. Our subsidiary Exothera, has the capabilities to do contract manufacture and development of these vaccines. We would therefore invite all developers of COVID-19 vaccine candidates to reach out to us. By combining expertise, we could bring a very interesting value proposition to the multiple funding initiatives being lauched at present.
Julien Declerck – Business Development Associate via BIOWIN PLATFORM
Covid-19 Portal von Forum Medtech Pharma
Beschaffungstelle des Bayerischen Landesamt für Gesundheit und Lebensmittelsicherheit (LGL)
BIO.NRW COVID-19 Informations- und Kontakt-Plattform
BIOWIN Wallonia Plattform
CoVex - A Coronavirus Explorer
COVID-19 Data Portal